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Components Enabling Development of the DOE Systems Biology Knowledgebase

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The DOE Office of Biological and Environmental Research (BER) has initiated or completed several key research projects and activities underpinning development of the DOE Systems Biology Knowledgebase (Kbase). First, with funding from the American Recovery and Reinvestment Act, a year-long R&D project was carried out to support the conceptual design and implementation planning necessary to develop Kbase. Completed in September 2010, this effort included a series of community planning workshops and five pilot projects. Together, these workshops and pilots informed the scientific objectives, software requirements, and design approaches detailed in the DOE Systems Biology Knowledgebase Implementation Plan, the final product of the R&D project. Also in late 2010, BER awarded funding to 11 university-led projects for research to develop new computational biology and bioinformatic methods to enable Kbase. Together, these activities—along with existing user-community data and resources—position BER to begin implementing Kbase.

Credit or Source: Office of Biological and Environmental Research of the U.S. Department of Energy Office of Science. science.energy.gov/ber

Citation(s):

U.S. DOE. 2011. Overview of Research Projects and Activities Underpinning Development of the DOE Systems Biology Knowledgebase, U.S. Department of Energy Office of Science. (p. 1) (website)

U.S. DOE 2012. Biosystems Design: Report from the July 2011 Workshop, DOE/SC-0141, U.S. Department of Energy Office of Science. (p. 15) (PDF)

Biological and Environmental Research Information System, Oak Ridge National Laboratory, genomicscience.energy.gov/ and genomics.energy.gov/.