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DOE Genomic Science Program: A Mission-Inspired Fundamental Research Approach

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The major aim of BER's Genomic Science program is to develop a predictive understanding of biological systems relevant to DOE mission challenges and to develop the commensurate tools.To date, the program has emphasized system-level investigations of individual organisms and the generation of data for constructing and evaluating predictive mechanistic models. Longer-term goals of the program are to develop a predictive understanding of complex biological communities and to improve the current technical and scientific infrastructure to address these problems. These specific goals and infrastructure improvements have been described and reiterated in several reports (American Academy of Microbiology 2006) and Genomic Science roadmaps, including Breaking the Biological Barriers to Cellulosic Ethanol: A Joint Research Agenda (U.S. DOE 2006), Carbon Cycling and Biosequestration: Integrating Biology through Systems Science (U.S. DOE 2008) and U.S. Department of Energy Office of Science Systems Biology Knowledgebase for a New Era in Biology (U.S. DOE 2009).

Credit or Source: Office of Biological and Environmental Research of the U.S. Department of Energy Office of Science.


US DOE. 2009. New Frontiers in Characterizing Biological Systems: Report from the May 2009 Workshop, DOE/SC-0121, US Department of Energy Office of Science. (website)

Prepared by the Biological and Environmental Research Information System, Oak Ridge National Laboratory, and