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Understanding Biological Capabilities at All Scales Needed to Support Systems Biology Investigations of Cellulosic Biomass (revised January 2008)

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Capabilities are needed to bring together the biological, physical, computational, and engineering sciences to create a new infrastructure for biology and the industrial biotechnology in the 21st Century. This figure depicts the focus of the Genomic Science program on building an integrated body of knowledge about behavior, from genomic interactions through ecosystem changes. Simultaneously studying multiple systems related to various aspects of the biofuel problem is powerfully synergistic because enduring biological themes are shared and general principles governing response, structure, and function apply throughout. Accumulating data as they are produced, the DOE Knowledgebase and computational environment will interactively link the capabilities and research efforts, allowing this information to be integrated into a predictive understanding. DOE’s technology programs can work with industry to apply such capabilities and knowledge to a new generation of processes, products, and industries.

Credit or Source: Office of Biological and Environmental Research of the U.S. Department of Energy Office of Science.


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U.S. DOE. 2009. U.S. Department of Energy Office of Science Systems Biology Knowledgebase for a New Era in Biology: A Genomics:GTL Report from the May 2008 Workshop, DOE/SC-113, U.S. Department of Energy Office of Science. (p. 3) (website)

Genomes to Life Program Roadmap, April 2001, DOE/SC-0036, U.S. Department of Energy Office of Science. (p. 1) (website)

U.S. DOE. 2014. DOE Genomic Science Program: Mission-Driven Systems Biology. 2014 Strategic Plan. U.S. Department of Energy Office of Science. (website)

Prepared by the Biological and Environmental Research Information System, Oak Ridge National Laboratory, and