In this system, all sites share a common data model but own a particular part of the biology domain (i.e., horizontal partitioning) and have separate data. Queries can be directed against one or multiple sites as needed using the network.
Credit or Source: Office of Biological and Environmental Research of the U.S. Department of Energy Office of Science. science.energy.gov/ber/
U.S. DOE. 2009. U.S. Department of Energy Office of Science Systems Biology Knowledgebase for a New Era in Biology: A Genomics:GTL Report from the May 2008 Workshop, DOE/SC-113, U.S. Department of Energy Office of Science. (p. 45) (website)