BER launches Environmental System Science Program. Visit our new website under construction!

U.S. Department of Energy Office of Biological and Environmental Research

BER Research Highlights

Advances in On-Line Resources for Microbial Research
Published: February 01, 2010
Posted: February 10, 2010

Substantial bioinformatics capabilities are required for systems biology approaches to solve DOE mission-related research problems in bioenergy and the environment. This is particularly true when microbiology is involved, as new technologies are generating vast amounts of data. DOE efforts to meet the scientific need for database systems are highlighted in the latest issue of Nucleic Acids Research. These include:

MicrobesOnLine (A. Arkin, Joint Bioenergy Institute and LBNL), a resource to integrate experimental data with genomic sequence data to understand microbial evolution and compare microbial functions under varied experimental conditions;

MiST2 (I. Zhulin, BioEnergy Science Center), which catalogs signalling proteins;

RegPrecise (D. Rodionov, LBNL), which catalogs transcription factor genes and will assist our understanding of cellular activity; and

IMG (N. Kyrpides, Joint Genome Institute), the Integrated Microbial Genomes resource provides new tools such as phylogenetic tools for comparative genomic analysis.

Taken together, these bioinformatics resources are leading to a more complete systems biological framework for microbial studies.

Reference: Nucleic Acids Research. January 2010, Vol. 38.

Contact: Susan Gregurick, SC-23.2, (301) 903-7672
Topic Areas:

  • Research Area: Genomic Analysis and Systems Biology
  • Research Area: Microbes and Communities
  • Research Area: DOE Joint Genome Institute (JGI)
  • Research Area: Sustainable Biofuels and Bioproducts
  • Research Area: DOE Bioenergy Research Centers (BRC)
  • Research Area: Computational Biology, Bioinformatics, Modeling
  • Research Area: Research Technologies and Methodologies
  • Cross-Cutting: Scientific Computing and SciDAC

Division: SC-33.2 Biological Systems Science Division, BER


BER supports basic research and scientific user facilities to advance DOE missions in energy and environment. More about BER

Recent Highlights

Jan 11, 2022
No Honor Among Copper Thieves
Findings provide a novel means to manipulate methanotrophs for a variety of environmental and in [more...]

Dec 06, 2021
New Genome Editing Tools Can Edit Within Microbial Communities
Two new technologies allow scientists to edit specific species and genes within complex laborato [more...]

Oct 27, 2021
Fungal Recyclers: Fungi Reuse Fire-Altered Organic Matter
Degrading pyrogenic (fire-affected) organic matter is an important ecosystem function of fungi i [more...]

Oct 19, 2021
Microbes Offer a Glimpse into the Future of Climate Change
Scientists identify key features in microbes that predict how warming affects carbon dioxide emi [more...]

Aug 25, 2021
Assessing the Production Cost and Carbon Footprint of a Promising Aviation Biofuel
Biomass-derived DMCO has the potential to serve as a low-carbon, high-performance jet fuel blend [more...]

List all highlights (possible long download time)