U.S. Department of Energy Office of Biological and Environmental Research

BER Research Highlights


New Microreactor Technology
Published: January 02, 2006
Posted: January 27, 2006

December 16, 2005, "This Week in Science" reports a Microreactor technology with potential for optimizing synthetic efficiency, particularly in preparing highly sensitive radioactive compounds for positron emission tomography (PET) imaging. This will allow the efficient synthesis and easy accessibility of radiotracers at the nuclear medicine imaging test site, and with minimal radiation exposure and significantly reduced radioactive waste generation. A team of UCLA scientists led by Dr. Hsian-Rong Tseng, in a five sequential process, achieved the synthesis of an [18F]fluoride-radiolabeled molecular imaging probe, commonly known as [18F]fluoro-deoxy-glucose ([18F]FDG), in an integrated microfluidic device. These results, which constitute a proof of principle for automated multistep syntheses at the nanogram to microgram scale, could be generalized to a range of radiolabeled substrates.

Contact: Prem Srivastava, SC-23.2, 3-4071
Topic Areas:

  • Legacy: Radiochemistry and Instrumentation
  • Legacy: Medical Applications

Division: SC-23.2 Biological Systems Science Division, BER
      (formerly SC-23.2 Medical Sciences Division, OBER)

 

BER supports basic research and scientific user facilities to advance DOE missions in energy and environment. More about BER

Recent Highlights

Aug 24, 2019
New Approach for Studying How Microbes Influence Their Environment
A diverse group of scientists suggests a common framework and targeting of known microbial processes [more...]

Aug 08, 2019
Nutrient-Hungry Peatland Microbes Reduce Carbon Loss Under Warmer Conditions
Enzyme production in peatlands reduces carbon lost to respiration under future high temperatures. [more...]

Aug 05, 2019
Amazon Forest Response to CO2 Fertilization Dependent on Plant Phosphorus Acquisition
AmazonFACE Model Intercomparison. The Science Plant growth is dependent on the availabi [more...]

Jul 29, 2019
A Slippery Slope: Soil Carbon Destabilization
Carbon gain or loss depends on the balance between competing biological, chemical, and physical reac [more...]

Jul 15, 2019
Field Evaluation of Gas Analyzers for Measuring Ecosystem Fluxes
How gas analyzer type and correction method impact measured fluxes. The Science A side- [more...]

List all highlights (possible long download time)