U.S. Department of Energy Office of Biological and Environmental Research

BER Research Highlights

Argonne Hosts Workshop on Software for Protein Crystallography and Demonstrates the Great Potential of Beamline Facilities at the Department of Energys Synchrotrons for Rapid, High Throughput Determination of Protein Structures
Published: December 04, 2002
Posted: December 16, 2002

In mid November some 70 scientists from the United States and Europe met at the Structural Biology Center (SBC) at the Argonne National Laboratory bringing together top developers of crystallographic software for structural biology. During three days of workshop there were six data collection training sessions using advanced software. The structure of a novel protein was determined as an example of the semi-automated approach to structure determination. Crystals of the protein were used to collect data on the SBCs undulator beamline at the Advanced Photon Source. The necessary data were collected in 20 minutes and processed in near real time. In just two hours the protein structure was determined and refined.

Contact: Roland F. Hirsch, SC-73, (301) 903-9009
Topic Areas:

  • Research Area: Structural Biology, Biomolecular Characterization and Imaging
  • Research Area: Structural Biology Infrastructure
  • Cross-Cutting: Education

Division: SC-23.2 Biological Systems Science Division, BER
      (formerly SC-73 Medical Sciences Division, OBER)


BER supports basic research and scientific user facilities to advance DOE missions in energy and environment. More about BER

Recent Highlights

Aug 24, 2019
New Approach for Studying How Microbes Influence Their Environment
A diverse group of scientists suggests a common framework and targeting of known microbial processes [more...]

Aug 08, 2019
Nutrient-Hungry Peatland Microbes Reduce Carbon Loss Under Warmer Conditions
Enzyme production in peatlands reduces carbon lost to respiration under future high temperatures. [more...]

Aug 05, 2019
Amazon Forest Response to CO2 Fertilization Dependent on Plant Phosphorus Acquisition
AmazonFACE Model Intercomparison. The Science Plant growth is dependent on the availabi [more...]

Jul 29, 2019
A Slippery Slope: Soil Carbon Destabilization
Carbon gain or loss depends on the balance between competing biological, chemical, and physical reac [more...]

Jul 15, 2019
Field Evaluation of Gas Analyzers for Measuring Ecosystem Fluxes
How gas analyzer type and correction method impact measured fluxes. The Science A side- [more...]

List all highlights (possible long download time)