U.S. Department of Energy Office of Biological and Environmental Research

BER Research Highlights


Winners of the Charles F. Kettering Prize by the General Motors Cancer Research Foundation.
Published: June 06, 2001
Posted: August 03, 2001

Two Biological and Environmental Research (BER) investigators, David E. Kuhl, M.D., Professor of Radiology, Chief of the Division of Nuclear Medicine, and Director of the PET Center at the University of Michigan Ann Arbor, MI; and Michael E. Phelps, Ph.D., Norton Simon Professor and Chair of the Department of Molecular & Medical Pharmacology at the UCLA School of Medicine, Los Angeles, CA; are among the five world-renowned scientists who have been recognized by the General Motors Cancer Research Foundation (GMCRF) for their seminal contributions to cancer research. Dr. Kuhl and Dr. Phelps are the co-winners of the Charles F. Kettering Prize for their involvement in the development of positron emission tomography (PET). The Kettering Prize recognizes the most outstanding recent contribution to the diagnosis or treatment of cancer. This high honor has been bestowed on a select number of the world's top scientists, seven of whom have subsequently won Nobel prizes. Dr. Kuhl and Dr. Phelps will receive a gold medal and will share a $250,000 award. The GMCRF Chairman Harry J. Pearce will present the Foundation's Charles F. Kettering Prize to Drs. Kuhl and Phelps at a ceremony that concludes GMCRF's Annual Scientific Conference, June 6 (1:30-3:30 PM) at the National Institutes of Health in Bethesda, Maryland. The conference, which focuses on "Mechanisms of Metastasis," will include lectures by Drs. Kuhl and Phelps describing their research. PET produces highly detailed cross-sectional pictures of small cancer deposits (metastases) that have been targeted after a simple intravenous injection of a radioactive glucose tracer, fluorine-18 fluorodeoxyglucose (FDG). In contrast to the more common CT scan, PET detection depends on tumor chemistry, not structure, and allows doctors and scientists to watch the chemistry and biology of the living human body in health and disease, thereby providing critical information that can help with earlier diagnosis and in staging a patient's cancer so that treatment can be chosen appropriately. Since its inception in 1947, the DOE/BER Medical Sciences program has supported nuclear medicine research including PET technology and radiotracer drug (e.g. FDG) development activities that have permitted insight into brain and heart physiology and pathophysiology previously unimaginable. The program has led to improved PET imaging modalities and to the improved diagnosis and treatment of patients with diverse illnesses such as cancer, Alzheimer's disease, and coronary artery disease. Both Dr. Phelps and Dr. Kuhl have long-standing BER research support involving PET and medical applications of PET for diagnosis and therapy.

Contact: P.C. Srivastava, SC-73, 3-4071
Topic Areas:

  • Cross-Cutting: Lectures, Awards, and Recognition
  • Legacy: Radiochemistry and Instrumentation

Division: SC-23.2 Biological Systems Science Division, BER
      (formerly SC-73 Medical Sciences Division, OBER)

 

BER supports basic research and scientific user facilities to advance DOE missions in energy and environment. More about BER

Recent Highlights

May 10, 2019
Quantifying Decision Uncertainty in Water Management via a Coupled Agent-Based Model
Considering risk perception can improve the representation of human decision-making processes in age [more...]

May 09, 2019
Projecting Global Urban Area Growth Through 2100 Based on Historical Time Series Data and Future Scenarios
Study provides country-specific urban area growth models and the first dataset on country-level urba [more...]

May 05, 2019
Calibrating Building Energy Demand Models to Refine Long-Term Energy Planning
A new, flexible calibration approach improved model accuracy in capturing year-to-year changes in bu [more...]

May 03, 2019
Calibration and Uncertainty Analysis of Demeter for Better Downscaling of Global Land Use and Land Cover Projections
Researchers improved the Demeter model’s performance by calibrating key parameters and establi [more...]

Apr 22, 2019
Representation of U.S. Warm Temperature Extremes in Global Climate Model Ensembles
Representation of warm temperature events varies considerably among global climate models, which has [more...]

List all highlights (possible long download time)