U.S. Department of Energy Office of Biological and Environmental Research

BER Research Highlights

Protein Data Bank Advisory Committee Meets, Assesses Impact of Accelerating Use of Synchrotrons for Protein Crystallography.
Published: April 25, 2001
Posted: August 03, 2001

The Protein Data Bank (PDB) for three-dimensional structures of proteins has been managed since 1999 by the Research Collaboratory for Structural Bioinformatics (RCSB), whose members are Rutgers University, the National Institute of Standards & Technology, and the University of California, San Diego (UCSD). The project receives funding from the National Science Foundation, the National Institutes of Health, and the BER program at DOE.

The PDB Advisory Committee has just held its annual meeting, this year at UCSD. The PDB received 2961 new structure depositions in calendar year 2000, and showed excellent performance in handling the depositions. There is, however, concern that the number of depositions will accelerate rapidly over the next few years, due to several large projects ("structural genomics") that will focus on high-throughput structure determination including the DOE synchrotron light sources. The Advisory Committee urged the PDB management to establish closer ties with the synchrotrons to ensure reliable and efficient transfer of new structural data.

The PDB has improved its international ties. The eleven-member advisory committee includes representatives from England, Japan, The Netherlands, and New Zealand. Structures can now be deposited to partners in England and Japan, and structural data can be retrieved from web sites.

Contact: Roland Hirsch, SC-73, 3-9009
Topic Areas:

  • Research Area: Structural Biology, Biomolecular Characterization and Imaging
  • Research Area: Structural Biology Infrastructure

Division: SC-23.2 Biological Systems Science Division, BER
      (formerly SC-73 Medical Sciences Division, OBER)


BER supports basic research and scientific user facilities to advance DOE missions in energy and environment. More about BER

Recent Highlights

May 10, 2019
Quantifying Decision Uncertainty in Water Management via a Coupled Agent-Based Model
Considering risk perception can improve the representation of human decision-making processes in age [more...]

May 09, 2019
Projecting Global Urban Area Growth Through 2100 Based on Historical Time Series Data and Future Scenarios
Study provides country-specific urban area growth models and the first dataset on country-level urba [more...]

May 05, 2019
Calibrating Building Energy Demand Models to Refine Long-Term Energy Planning
A new, flexible calibration approach improved model accuracy in capturing year-to-year changes in bu [more...]

May 03, 2019
Calibration and Uncertainty Analysis of Demeter for Better Downscaling of Global Land Use and Land Cover Projections
Researchers improved the Demeter model’s performance by calibrating key parameters and establi [more...]

Apr 22, 2019
Representation of U.S. Warm Temperature Extremes in Global Climate Model Ensembles
Representation of warm temperature events varies considerably among global climate models, which has [more...]

List all highlights (possible long download time)